PYH Newsletter: Why Can’t I Sleep or Think Straight Lately? (Hint: It’s Not You…)


Dr. Valorie

October 28th, 2025

Can't Sleep, Can't Think: Why Hormones? WHY??!!

Because You Can’t Handle the Hormones!

In this issue

What's Happening


Ready to Spin the Wheel of Sleep Symptoms with me?


Simon Says


What Happens to Your Brain When Your Hormones Start to Change?


My Menopause

What's Happening?

Between consults, newsletters, podcasts, social media, and everyday life, I kept hearing the same thing:

“I just wish there was a place to talk about this with someone who actually understands.”

So that’s why we built: The Progress Your Hormones Community.

Not a random forum, but a space where I am there reading, answering, guiding, and helping you make sense of what your hormones are doing in real time and women’s health and longevity.


You don’t have to be a “group person” to belong.


Some women post.


Some never say a word, they just read, watch, and quietly apply what they need.


Both are welcome.


It’s simply a place where you don’t have to navigate this stage alone. Where you can be understood, and supported instead of guessing and Googling in silence.


If you read that and thought, “That is exactly what I need…” The Progress Your Hormones Community is open to you.

Missed a Newsletter? Or want to read any past Progress Your Hormones Newsletter?


Check out our Library: archive of all past newsletters

Newsletter Library

I do not have AI write my articles.

Why?

Bc I like spending hours writing.

Bc AI does not sound like me and I hate the werid dashes it puts in

Bc I find AI is not accurate (seriously, you need to fact check anything you ask AI)

Bc my AI tends to coddle me

Bc I just don’t feel like it is authentically me.

- Xo DrValorie

Ready to Spin the Wheel of Sleep Symptoms with me?

Second Wind Sherri

Remember from our last newsletter the long, long list of sleep issues that we women can have when going through menopause and perimenopause?


Well, along with the list I put together in the last newsletter, I got more messages and responses to other sleep conditions women deal with. This list is getting long…

  • Second wind before bed
  • Hypnic jerks when falling asleep
  • Waking up not rested, even though feeling like you slept
  • Dry mouth
  • Snoring
  • Restless leg
  • Jaw clenching

Along with my original list:

  • Can't fall asleep
  • Waking in the middle of the night, wide awake for hours
  • Waking up multiple times all night
  • Waking up to urinate all night: newsletter #15
  • Waking up hot and sweaty
  • Waking up anxious
  • Waking up with heart palpitations
  • Waking up with gloom and doom
  • Waking up with racing thoughts
  • Waking up with muscle cramps (feet and calves)
  • Waking up with a headache
  • Itchy at night
  • Nightmares

Do any of you have other sleep issues that I forgot to put in here? Message or email me back to this and let me know!


Let's Spin the Wheel of Sleep Symptoms…


Second Wind Before Bed:

Tired during the day? But then eveningtime comes, when you should be getting ready for bed, you start to feel more awake?


Everyone else may be in bed, and you feel more alert, more relaxed.


So what do you do? You stay up too late, don't get enough sleep, and then you're tired the entire next day. And I get it, if you could go to bed at a 'reasonable time', you would.


Meet Second-Wind Sherri:

'Everyone is in bed. Everyone, that is, except me. Me, myself, and I. This is so nice, I just finished up some laundry, sent a few emails, put a few things away, and after sending some hilarious memes back and forth with my besie, I know what I should do.


I should get ready for bed. But I don't feel sleepy at all. I actually feel kinda good.


Go to sleep? No, I would rather shop online, scroll on my phone, grab some snacks, and watch some fun shows.

Why am I so awake at 9:30pm? I have to wake up so early to get my high schooler, Lucas, to his early-morning faith class. I have to wake up at 5am tomorrow. And even Lucas is getting ready for bed.


My high school son goes to bed before me!


I don't want to go to sleep. I don't even think I could go to sleep.


Ugh, you would think I would be so ready for bed, considering I am sooooo tired in the morning and during the day.


Okay, I am not perfect with sleep hygiene. I do have one of those trendy caffeinated fuzzy drinks in the morning. And I have another one again in the afternoon…after my nap.


Yes, I do take a nap in the afternoon. I know it's bad, but I am so tired in the afternoon before I pick up Lucas. My nap is only an hour, and I work from home, so I get everything done (very well) by that time. Then we have baseball practice and gotta get dinner for everyone. Next thing I know, it's 8:30pm and I am starting to feel more energy. By 9:30pm, I don't want to go to sleep.


Yes, I know I am creating a vicious cycle of staying up too late, not getting enough sleep, having too much caffeine, using electronic devices before bed, and eating before bed. Yes, that is an F for sleep hygiene. But I feel like I can't help it. I feel good when the sun goes down and everyone else is in bed. But I sure don't feel good the next day:(‘


What is going on with Sherri?

Is she sabotaging her day because of her late-night activities?


It's not like she is going out, drinking, or partying like a frat boy. She just stays up late snacking, tidying up, watching fun shows on her phone, and texting with her best friend.


We all know that sleep is foundational for health, clarity, well-being, and even your waistline (yes, not sleeping can make you gain weight, not late-night snacking).


So what happens when you can't sleep at night? Or what happens when you feel best at night? You feel good at night, why would you waste that?


Let's get some more background on Sherri.


Sherri is 48 years old, and her sleep antics have not always been this way. Over the last 4 years, she has been staying up later and later. Why is that?


It is because of her cortisol.


As I always say…


Cortisol, My Frenemy:

Cortisol, I can't live without you (no, really, you cannot live without cortisol). And I can't live with you (at least when you are messing with my waistline, my sleep, and my mood).


Trust me, cortisol does not have it out for you.

Cortisol is really trying to help us. But when dysregulated, it can wreak havoc on our sleep patterns.


And guess what?


Cortisol is not directly responsible for the 'second-wind' issue.


In fact, we are blaming cortisol when other players are orchestrating this process behind the scenes.


Master-Blaster:

Don't shoot the messenger, aka, cortisol.


Cortisol is blamed for everything, from belly fat, puffiness, bloating, irritability, and sleep issues.

But who is behind this?


Estrogen and progesterone are not as sweet as they seem. When your hormones start to change in perimenopause and menopause, cortisol can go on a wild sleeplessness spree.


When estrogen and progesterone decline, they can no longer buffer cortisol as they used to. This is where you see a disrupted diurnal curve for cortisol.


Normally, in a perfect world, cortisol is highest in the morning, so we wake up bright-eyed and bushy-tailed. Then cortisol declines throughout the day and is lowest at night, so we can sleep.


Sleep is foundational. It helps our cells repair, supports cellular turnover, is essential for brain and heart health, and even helps with immune function.


So let's look at this from a 'Sherri-angle'. Sherry's estrogen and progesterone have both dropped. In fact, at this point in her life, her progesterone levels are most likely nonexistent. And her estrogen levels are declining with little spurts throughout the month.


If estrogen and progesterone are not there to harness cortisol, it can rise at night. Elevated cortisol levels at night are making Sherri feel alive, with more energy.


If cortisol levels are going up at night, they are going to be crashing in the morning. That is why it is so hard for Sherri to wake up, and it makes her tired during the day.


What do we do for the Sherri(s) of the world?


If you see yourself as Second-Wind-Sherri, you are not alone. This pattern can be common when the hormones start to shift in perimenopause and menopause. And there are safe, natural options to help with sleep struggles.


Understanding why you feel wired at 9:30 pm and wrecked at 7 am is step one, but the relief comes from what you do next.


The paid version continues with exactly how I treat “Second-Wind Sherri” in real life: HRT options, timing, doses, and non-HRT protocols that actually work.


Unlock every full article, protocol, and deep-dive for $9/month or $99/year

If you’d like to dive into the science behind why this happens and what you can actually do about it (including natural hormone, nutrient, and herbal support), join the paid version of the Progress Your Hormones Newsletter.

Upgrade to the full newsletter here and get the rest of the story.

Simon Says:

Simon Says:

Buy the Halloween candy you don’t even like, you’re far less likely to indulge. And if you do eat some, pair it with protein… and no, peanut butter cups don’t count.

Where Is My Brain?

What Happens to Your Brain When Your Hormones Start to Change?

Dr. Valorie Davidson

Brain Before Body

Even before you miss a period or get a hot flash, your brain is already aware of the changes that are happening to your hormones in perimenopause and menopause.


That is why many early symptoms of hormonal changes are missed and/or blown off as 'something else'.


Early symptoms of hormonal changes impacting your brain:

  • Brain fog
  • Dropping words
  • Trouble finding the right word
  • Mood swings
  • Irritability
  • Trouble focusing
  • Apathy or emotional flatness

These early symptoms are technically 'in your head', but not in the common cliche sense. Hormonal changes in perimenopause and menopause can literally affect your head/brain.

Estrogen and progesterone can act as brain chemicals.

Your brain has relied on these hormones for decades to help regulate mood, sleep, stress response, and mental clarity.

Now that your hormones are shifting, your brain feels it. Which is why you can feel angst, mood swings with anger, lack of clarity and focus, poor sleep, and memory. This can happen even before you miss your first period.


Estrogen and Progesterone as Neuro-Drugs:
Estrogen and Progesterone affect A LOT. We all know this. But did you know that estrogen and progesterone also directly affect brain chemistry?

Estrogen can enhance:

  • Dopamine: can help increase motivation, focus, and drive
  • Serotonin: can help boost mood
  • Acetylcholine: can help with cognition, memory, and even how the words come out of our mouths
  • Glutamate: can help with learning
  • GABA: can help offset angst

Progesterone and its metabolite, allopregnanalone, can enhance and help:

  • GABA: Can help with calming, promote sleep, be less reactive, and can offset cortisol.
  • Neuroprotective and anti-inflammatory for the brain (neurons and myelin).

Our brains are pretty amazing, and over time, will try to compensate for the hormonal decline. The brain will upregulate hormone receptors as a compensatory mechanism for lower hormone levels.


The brain has been shown to adapt over time.


But what about long-term brain health and function after the hormones have declined?

  • Female sex and hormone changes/decline are linked to dementia and Alzheimer's vulnerability.
  • Estrogen can increase brain protection. It can help with brain energy (glucose/fuel) and acts as an antioxidant to reduce inflammation and oxidative damage. Protect blood vessels from stiffness and damage. It can also influence amyloid metabolism and clearance.

Other conditions linked to hormonal decline:

  • Heart disease/conditions increase in women after menopause.
  • Diabetes risk increases after menopause.
  • Weight gain and visceral fat/adipose tissue increase after menopause.
  • Bone density decline and osteoporosis risk increase after menopause.

Now this is where it can start to look like the 'Chicken and Egg' conundrum.

  • Hormonal changes in peri and menopause can cause sleep issues. Sleep debt and poor sleep quality increase risk for dementia and Alzheimer's. So is it poor sleep or a drop in hormones?
  • Weight gain, cravings, and poor energy levels can cause more visceral fat and increase the risk of inflammation and diabetes. Is it the hormones or the weight gain and sedentary lifestyle increasing cardiovascular disease, inflammatory conditions, diabetes, and insulin resistance?

Overall, we can all agree that hormonal change/decline in perimenopause and menopause can increase your risk for chronic diseases such as heart disease, dementia/Alzheimer's, diabetes, and inflammatory conditions.


Not to mention, it can affect our daily lives —sleep, mood, libido, weight, hair/skin/nails, memory, motivation, and focus. I could go on and on…


So what can we do about it? What can we do for our brains?

HRT can be powerful, but it's not the only tool. Many women need a combination of hormone therapy and non-hormonal strategies to protect the brain, heart, bones, metabolism, and daily quality of life.

This article is about brain health and hormones. So, for this next part, let's talk about HRT and non-HRT options to help with brain health, both acute and long-term.


Lost My Brain Lisa:

'Okay, got my keys, got my bag, got my wallet… where is it?


Where is it??!!!


I can't find it, WHERE IS MY BRAIN?!


Bc if I can't find my brain, it's going to be Groundhog Day at work today.


I can't follow along in conversations. I forget my colleagues' names after asking the same question several times.


My co-worker winked at me yesterday and said, 'Went a little too hard last night? HaHa'. Oh my gosh, I did not!‘


Lisa is not alone when it comes to our cognition/brain and hormonal changes:

  • Foggy brain: feels like your head is stuffed full of cotton instead of lipids, myelin, neurons…
  • Recall Gone: can't find the right word, cannot retrieve names
  • Forget Focus: scattered attention, easily distracted = squirreling
  • Moody: sad, mad, worried
  • Word loss: dropping words mid-sentence or the words come out sounding strange, or saying the wrong word.
  • Repeater: repeating the questions
  • Hard to multitask
  • Trouble keeping up with conversations
  • Getting overwhelmed by too much stimuli

Not all women are Lisa, but many can relate to some of her symptoms. Her brain is trying to adapt to the decline and changes in her progesterone and estrogen.


When it comes to hormones, we want to think about acute goals and long-term brain health.


Speaking from experience and the many Lisa(s) I have worked with since 2004, when it comes to hormonal changes, we want our BRAIN BACK!

Overall, we can all agree that hormonal change/decline in perimenopause and menopause can affect your daily life and increase your risk for chronic diseases.

So what can we do about it? What can we do for our brains?


The free portion stops here. The “what to do about it” section is for paid members: $9/month or $99/year.

→ Subscribe to the full version of the newsletter to read the rest.

My Menopause

After our live event/presentation on supplements for women last week, I realized there are so many supplements available, and it can be confusing to know which to take.

I’ll admit, I take a lot of supplements. But it can be overwhelming to see so many great supplements advertised, recommended, and labeled as essential for health.


And everyone I talk to has supplements everywhere, pantries, tables, bathrooms, counters, desks, and even cars. And many of the people/patients I speak to say they do not take them all regularly.

So this got me thinking, I want to create a list, a short list, a doable list, for foundational supplements for women in perimenopause and menopause.


There are a lot of great supplements to take, but I wanted to make this list ‘doable’ because consistency is where you get the benefit.

Vitamin D3 + K2

  • Helps with bone, immune, inflammation, and hair
  • You can test your blood work for dosing. Ideally, on blood work, I like to see the vitamin D levels between 55-85 ng/ml. For most women, that is 5000 IU daily.
  • Bonus: Take your vitamin D3 with K2.
    • Vitamin D increases the absorption of calcium. Vitamin K2 will tell the body to put calcium into bone and away from arteries.

Magnesium (glycinate and/or L-threonate )

  • Helps with sleep and is a cofactor for over 300 enzymatic reactions that control energy production, hormone metabolism, neurotransmitters, and muscle contraction.
  • 200–400 mg at night

Omega-3 (EPA + DHA)

  • Helps with inflammation, brain health, joint health, and cardiovascular health.
  • 1000-2000mg daily

Creatine

  • Creatine helps women maintain muscle, support bone, and brain health, and can help with energy
  • 3–5 g/day
  • Don’t take it if you have kidney issues/conditions
  • Stay hydrated (drink plenty of water) as creatine pulls water into muscle cells.

Collagen

  • Helps support skin elasticity, joint comfort, hair, and bone structure.
  • Not a replacement for dietary protein.

Protein and Fiber: I know these aren't exactly supplements, but I have to include how important protein and fiber are for women.


Protein:

  • Protects muscle (bc estrogen decline can accelerate muscle loss)
  • Stabilizes blood sugar
  • Protein is made of amino acids, which are the raw materials the body uses to build and repair everything (muscle, connective tissue, enzymes, immune cells, hormones, and neurotransmitters)
  • There are so many experts with varying opinions about how much protein women should be having. But if you are like me and have a hard time eating that much protein, aim for 1.0-1.2 grams of protein per kilogram of body weight per day.
    • (To convert pounds to kilograms, you divide by 2.2)

Fiber:

  • Stabilizes blood sugar and helps with satiety
  • Supports gut health by feeding good bacteria and helping them make anti-inflammatory compounds to repair the gut lining.
  • Helps with detoxification
  • At least 25 grams per day. But if you can get up to 35 grams of fiber daily, that is amazing.

Now I am sure many of you have other supplements you love to take. Please feel free to reach out and tell me about them, as this list is more of a foundation to start from.

Dr.Valorie

Disclaimer

All content found in this newsletter, including text, images, audio, video, or other formats, was created for informational purposes only. The purpose of this website and blog is to promote consumer/public understanding and general knowledge of various health topics. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please consult your healthcare provider with any questions or concerns you may have regarding your condition before undertaking a new healthcare regimen. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. If your healthcare provider is not interested in discussing your health concern regarding this topic, then it is time to find a new doctor.

1140 10th St Ste 212, Bellingham, WA 98225
Unsubscribe · Preferences

Progress Your Hormones Newsletter

A newsletter about hormones, HRT, and Dr. Valorie’s personal experience with menopause and rhythmic dosing.

Read more from Progress Your Hormones Newsletter

VIEW IN BROWSER Dr. Valorie November 25th, 2025 The Thanksgiving Effect In this issue What's Happening The Thanksgiving Effect Simon Says My Menopause What's Happening? Hi everyone, I’ve made a free video minicourse called The In-Betweener Minicourse. It’s for anyone who is almost out of perimenopause but not quite in menopause, where you feel stuck in the middle. This phase in life is often overlooked, misdiagnosed, and/or mistreated. If this sounds like you, just click on the link....

VIEW IN BROWSER Dr. Valorie November 25th, 2025 The Thanksgiving Effect In this issue What's Happening The Thanksgiving Effect Simon Says My Menopause What's Happening? Hi everyone, I’ve made a free video minicourse called The In-Betweener Minicourse. It’s for anyone who is almost out of perimenopause but not quite in menopause, where you feel stuck in the middle. This phase in life is often overlooked, misdiagnosed, and/or mistreated. If this sounds like you, just click on the link....

VIEW IN BROWSER Dr. Valorie November 11th, 2025 Holiday Havoc on the Liver In this issue What's Happening My Liver, What a Nag! Simon Says Katy Feels Krappy My Menopause What's Happening? This is the 17th edition of the Progress Your Hormones Newsletter! Those of you from #1 to now, I am so grateful to you all. And those of you who are new, welcome to my newsletter. A place about women’s health and longevity, HRT, menopause, perimenopause, and anything about hormonal health. Anything you want...